Initiation, Elongation, and Termination of Translation

Translation:

Initiation:
-In the ribosome, mRNA and tRNA come together
-In the ribosome, there is the big subunit and the small subunit
-Bigger subunit joins the smaller subunit, the first a.a. tRNA, and mRNA (initiation complex)
-The start codon for the protein is AUG (methionine)

Elongation:
-addition of codons/amino acids that will eventually make up the polypetide (final result)
-three sites: APE (A-entrance, P-prison, G-exit)
-amino acids can bind in the A-site and P-site
-initiating tRNA binds to the P site, then binds to an amino acid brought by the next tRNA (in the A-site)
-After the amino acids bind, the first initiating tRNA is released from the P site (prison)

Termination:
-The process of amino acid binding is continued until a stop codon is brought to the A site on the mRNA
-These stop codons are: UAA, UAG, and UGA